What is Xifaxan used for?      

Xifaxan is a nonsystemic (does not get into your bloodstream) antibiotic used to treat diarrhea caused by eating food or drinking fluids that have been contaminated with germs called bacteria.

Who should not take Xifaxan? 

·       If you have fever and/or bloody stool you should not take Xifaxan and you should speak to your doctor.

·       Xifaxan should not be used to treat a form of diarrhea known as dysentery.

·       Do not take Xifaxan if you have ever had an allergic reaction to any of the group of antibiotics known as ?rifamycins? such as rifampin or if you are allergic to any ingredient in Xifaxan.

·       Xifaxan is not approved for use in children under 12 years of age.

Special Warning(s) with Xifaxan:    

Sometimes viruses rather than bacteria may cause diarrhea. Xifaxan, like all other antibiotics, does not kill viruses.  You should contact your doctor or health care professional if you think your condition is getting worse or is not improving after 24 - 48 hours (1 ? 2 days) while taking Xifaxan.

What should I tell my health care provider?  

Tell your health care provider if you are pregnant, are trying to become pregnant, or are breast-feeding

Xifaxan has not been shown to cause interactions with other drugs.  However, it is always important that you inform your doctor or healthcare professional of any other medications you are taking before starting treatment with Xifaxan.

What are some possible side effects of Xifaxan? (This list is NOT a complete list of side effects reported with Xifaxan.  Your health care provider can discuss with you a more complete list of side effects.) 

Some common side effects with Xifaxan include:

• flatulence (gas)
• headache
• stomach pain
• sensations of needing to empty the bowel
• urgent bowel movements
• nausea

For more detailed information about Xifaxan, ask your health care provider or pharmacist.